The Cancer Letter

The leading source for information on the issues that shape oncology since 1973

NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprises
New NOFO aims to shrink applications by 40%

Cancer Policy

HHS announces initiative to improve breast cancer screening and early detection

CDC Deputy Director Jennifer Shuford resigns

Cost of family insurance plans rose for workers in 2026, KFF survey finds

Professional societies, cancer advocacy groups urge NIH to withdraw proposed changes to peer-review process

Trump signs executive order to establish the NIH Women’s Health Division and task force

Letai announces: NCI met FY26 goal of full funding payout

Clinical Roundup

ASTRO updates guideline on shorter-course radiation therapy for localized prostate cancer

Tarlatamab + durvalumab extend median OS for patients with ES-SCLC, phase III DeLLphi-305 trial finds

Divarasib monotherapy improves OS in previously-treated KRAS G12C-mutated lung cancer, phase III trial finds

Arcotatug tavatecan improves OS and PFS in patients with advanced gastric cancer, phase III study finds

Perioperative Imfinzi + Padcev improves EFS, OS, in MIBC, phase III trial finds

Perioperative apalutamide in high-risk localized or locally advanced prostate cancer substudy supports reduced risk of metastasis and death

In The Clinic

Cancer vaccine policy in limbo as CDC keeps canceling advisory meetings

Regulatory News
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